A Bensalem girl who has been through 40 brain surgeries and two strokes at the Children’s Hospital of Philadelphia is missing a very special friend.

Niki Dougherty-Ramirez says her 13-year-old daughter Bryanna has had her “well loved” Minnie Mouse doll through each medical episode since being an infant.

Bryanna’s Minnie. The doll no longer has the CHOP wristband.

Initially, Ramirez and her husband thought buying the doll would be a waste of $6. Bryanna proved them wrong.

“She literally, from that day, did not put Minnie down,” Ramirez told Fox 29.

Bryanna and her sisters were born with a medical condition, according to Ramirez.

“Their skull is too small for their brain, and it pushes their brain down into their spinal cord.”

But now Minnie is missing and the search is on. A Facebook post asking for help has more than 50,000 shares.

“My daughter is beyond heart broken. I hope we can find her. I cant imagine having to send her into the OR again without her Minnie.”

Minnie was last seen at 6 p.m. Saturday night at the Chick-fil-A in Neshaminy Mall. Attempts to search through nearby trash were unsuccessful.

If anyone should stumble across Minnie in their travels, they should immediately contact Niki Dougherty-Ramirez through Facebook here.